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  1. For depression or anxiety: Adults and children 12 years of age and older—At first, 75 milligrams (mg) once a day or in divided doses during the day. Your doctor may adjust your dose as needed. However, the dose is usually not more than 150 mg per day. Children younger than 12 years of age—Use is not recommended.

  2. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. For topical dosage form (cream):

  3. 14 Φεβ 2024 · Major depressive disorder: For major depressive disorder (unipolar) and treatment-resistant depression, the initial dose typically ranges from 25 to 75 mg at bedtime. This dosage is gradually increased every third day by 25 to 50 mg until reaching a daily dosage of 100 to 300 mg.

  4. 11 Ιαν 2024 · Initial dose: 75 mg orally once a day. Maintenance dose: 75 to 150 mg orally once a day or in divided doses; patients with very mild disease may be adequately controlled with 25 to 50 mg per day. Maximum dose: 150 mg/day.

  5. Dosage range: 25-300 mg/day PO, up to 150 mg/day as single dose. If dose exceeds 150 mg/day, divide q12hr. Dosing considerations. May give qHS to decrease daytime sedation; Insomnia...

  6. 3 Ιουν 2022 · The usual optimum dose range is 75 mg/day to 150 mg/day. In more severely ill patients higher doses may be required with subsequent gradual increase to 300 mg/day if necessary. Additional therapeutic effect is rarely to be obtained by exceeding a dose of 300 mg/day.

  7. 5 Οκτ 2022 · For most patients with illness of mild to moderate severity, a starting daily dose of 75 mg is recommended. Dosage may subsequently be increased or decreased at appropriate intervals and according to individual response. The usual optimum dose range is 75 mg/day to 150 mg/day.

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