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  1. 15 Σεπ 2020 · Risk factors for drug-induced AF/AFL are drug specific: adenosine (premature atrial complexes), alcohol (dose >30 g/d, ≥1–3 drinks per day; withdrawal syndrome), and dobutamine (advanced age, prior AF, heart failure). 1 Strategies for prevention include administering the lowest effective dose of AF/AFL–inducing drugs, 1 minimizing or ...

  2. 15 Σεπ 2020 · Awareness of drugs that may cause arrhythmias and knowledge of distinct arrhythmias that may be drug-induced are essential for clinicians. Consideration of the possibility that a patient’s arrythmia could be drug-induced is important.

  3. 13 Οκτ 2020 · Numerous antiarrhythmic agents, antimicrobial drugs, psychotropic medications, and methadone, as well as a growing list of drugs from other therapeutic classes (neurological drugs, anticancer agents, and many others), can prolong the QT interval and provoke torsades de pointes.

  4. Mechanisms of arrhythmias are well known for some medications but, in other instances, remain poorly understood. For some drug-induced arrhythmias, particularly torsades de pointes, risk factors are well defined. Modification of risk factors, when possible, is important for prevention and risk reduction.

  5. 21 Σεπ 2020 · The following are key points to remember from this American Heart Association Scientific Statement on drug-induced arrhythmias: Bradycardia: Sinus node automaticity is suppressed by drugs that inhibit sympathetic nervous system activity (beta-blockers) or stimulate the parasympathetic nervous system (neostigmine, pyridostigmine).

  6. 15 Σεπ 2020 · Some drug-induced arrhythmias (bradyarrhythmias, atrial tachycardia, atrioventricular node reentrant tachycardia) are significant predominantly because of their symptoms; others (monomorphic...

  7. 17 Ιαν 2021 · The drug-induced arrhythmias can be caused by conditions leading to altered drug pharmacokinetics and increased plasma concentrations and metabolites having proarrhythmogenic effects, as well...

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