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1 Δεκ 2011 · In this review we summarize data on biological effects of the three most commonly used lipophilic drug vehicles dimethylsulfoxide (DMSO), propylene glycol (PG) and ethanol....
16 Απρ 2024 · As defined by the United States Pharmacopeia (USP), the solubility of drugs is expressed as the amount of solvent needed per unit of solute. Additionally, solubility is quantified by the molality, molarity, and percentage of the solvent. As shown in the Table, solubility is categorized into seven groups.
12 Σεπ 2022 · The units of solubility can be provided in mol/L or g/L. Factors that affect solubility include the concentration of the solute, temperature of the system, pressure (for gases in solution), and polarity of the solute and the solvent.
Drug solubility is defined as the amount of drug that passes into solution when an equilibrium is established between the drug solute in solution and any excess, un-dissolved drug to produce a saturated solution at a specified temperature [2].
28 Ιαν 2021 · Various techniques available to improve the solubility of poorly soluble drugs by physical and chemical modifications.
1 Ιαν 2009 · Introduction: Deep eutectic solvents comprising or acting as solvents of active pharmaceutical ingredients (API-DES) emerged as promising alternatives to improve therapeutic efficiency, with...
Identify the descriptive terms for solubility, their meaning, and their percent value. Recognize factors that affect solubility. Calculate the solubility of poorly soluble strong electrolytes by using K sp values.
