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Citicoline inhibits apoptosis associated with cerebral ischemia and several models of neurodegeneration. 1 – 3 It is also able to potentiate neuroplasticity and is a natural precursor of phospholipid synthesis, chiefly phosphatidylcholine, or rather serves as a choline source in the metabolic pathways for biosynthesis of acetylcholine. 1 ...
- Neuroprotective Properties of Citicoline: Facts, Doubts and Unresolved ...
In spite of the negative results of recent pivotal studies...
- Citicoline: pharmacological and clinical review, 2022 update
Citicoline: pharmacological and clinical review, 2016...
- Neuroprotective Properties of Citicoline: Facts, Doubts and Unresolved ...
27 Δεκ 2022 · This review is focused on the main indications of the drug, as acute stroke and its sequelae, including the cognitive impairment, and traumatic brain injury and its sequelae. There are retrieved...
In spite of the negative results of recent pivotal studies in acute ischaemic stroke and traumatic brain injury, there is continuing interest in the neuroprotective properties of citicoline. The drug is non-toxic, and numerous preclinical data support the view that it displays neuroprotective properties.
12 Ιουλ 2022 · One of these new drugs is citicoline, which could provide neurovascular protection and repair effects. Objectives: The objective of this randomized, single-blind experimental study was to evaluate whether the treatment with Rischiaril ® Forte was able to restore intracortical excitability measures, evaluated through transcranial magnetic ...
30 Νοε 2022 · Citicoline: pharmacological and clinical review, 2016 update. Rev Neurol 2016; 63 (Supl 3): S1-S73), incorporating 176 new references, having all the information available in the same document to facilitate the access to the inf …
23 Δεκ 2016 · This review is focused on the main indications of the drug, as acute stroke and its sequelae, including the cognitive impairment, and traumatic brain injury and its sequelae. There are retrieved the most important experimental and clinical data in both indications.
1 Οκτ 2015 · Citicoline is a multimodal drug that exhibits neuroprotective and neuroregenerative effects in a variety of experimental and clinical disorders of the central nervous system, including acute and chronic cerebral ischemia, intracerebral hemorrhage, and global cerebral hypoxia.