Αποτελέσματα Αναζήτησης
27 Δεκ 2022 · This review is focused on the main indications of the drug, as acute stroke and its sequelae, including the cognitive impairment, and traumatic brain injury and its sequelae. There are retrieved...
26 Μαΐ 2018 · Mechanism of Action. Citicoline consumption promotes brain metabolism by restoring phospholipid content in the brain and regulation of neuronal membrane excitability. It also influences the mitochondria or energy factories of the brain cells and found to improve memory function.
23 Δεκ 2016 · This review is focused on the main indications of the drug, as acute stroke and its sequelae, including the cognitive impairment, and traumatic brain injury and its sequelae. There are retrieved the most important experimental and clinical data in both indications.
In spite of the negative results of recent pivotal studies in acute ischaemic stroke and traumatic brain injury, there is continuing interest in the neuroprotective properties of citicoline. The drug is non-toxic, and numerous preclinical data support the view that it displays neuroprotective properties.
Recent studies on the possible role of citicoline in increasing sirtuin 1 (SIRT1) expression were assessed. Some personal studies were also considered, such as the VITA study and the IDEALE study. Results. Administered by both oral and intravenous routes, citicoline is converted into two major circulating metabolites, cytidine and choline.
Medicines containing citicoline (cytidine-diphosphocholine) as an active principle have been marketed since the 1970s as nootropic and psychostimulant drugs available on prescription. Recently, the inner salt variant of this substance was pronounced ...
23 Δεκ 2016 · Band densitometry analysis for PARP by western blotting in different groups of rats in the infarct zone and penumbra zone 12 and 24 h after ischaemia. a p < 0.05; b p < 0.025; c p < 0.0001....
