Αποτελέσματα Αναζήτησης
23 Δεκ 2016 · This review is focused on the main indications of the drug, as acute stroke and its sequelae, including the cognitive impairment, and traumatic brain injury and its sequelae. There are retrieved the most important experimental and clinical data in both indications.
27 Δεκ 2022 · This review is focused on the main indications of the drug, as acute stroke and its sequelae, including the cognitive impairment, and traumatic brain injury and its sequelae. There are retrieved...
The most recent study of this kind indicated that liposomal citicoline is more neuroprotective than the equivalent intravenous dose of the free drug which, in turn, is more neuroprotective than the equivalent intraperitoneal dose. Although other explanations may be speculated upon, the aforementioned result is compatible with the idea that ...
28 Ιουλ 2012 · The primary objective of this study was to assess the effects of citicoline compared with placebo on the recovery of patients with moderate-to-severe acute ischaemic stroke at 3 months, after having received 2000 mg daily for 6 weeks.
This systematic review supports some benefits of citicoline in the treatment of acute ischemic stroke. But, on top of the best treatment available (rtPA), citicoline offers a limited benefit.
16 Δεκ 2010 · Forty-two studies of citicoline treatment in animal models of cerebral ischemia were identified. Fifteen studies on focal ischemia were analyzed describing procedures involving 313 animals and reporting the effect of citicoline on infarct size (n=313) or functional outcome (n=104).
These studies claim that citicoline treatment reduces size of infarct (region of dead tissue), decreases free fatty acid concentration, decreases neurologic deficits, restores animal learning performance, reduces glutamate‐mediated injury, preserves phosphatidylcholine levels, and improves neuronal survival .
