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  1. Here, we test citicoline effectiveness as an adjuvant therapy in major depression. Method: A double-blind randomized trial was designed on 50 patients with major depressive disorder who were under treatment with citalopram.

  2. 1 Ιαν 2017 · Results Studies showed that post-stroke depression (PSD) could be treated with antidepressant therapy, as well as supportive drugs such as citicoline or choline alfoscerate, which may have ...

  3. In spite of the negative results of recent pivotal studies in acute ischaemic stroke and traumatic brain injury, there is continuing interest in the neuroprotective properties of citicoline. The drug is non-toxic, and numerous preclinical data support the view that it displays neuroprotective properties.

  4. 2 Νοε 2021 · The aim of this study was to investigate whether a therapy based on nootropic drugs could be at least as effective in the reduction of anxiety and depressive symptoms as an antidepressant therapy in patients with PSD.

  5. 27 Δεκ 2022 · This review is focused on the main indications of the drug, as acute stroke and its sequelae, including the cognitive impairment, and traumatic brain injury and its sequelae.

  6. 7 Απρ 2018 · All antidepressants were more efficacious than placebo in adults with major depressive disorder. Smaller differences between active drugs were found when placebo-controlled trials were included in the analysis, whereas there was more variability in efficacy and acceptability in head-to-head trials.

  7. A double-blind randomized trial was designed on 50 patients with major depressive disorder who were under treatment with citalopram. Patients were allocated to 2 groups and received citicoline (100 mg twice a day) or placebo as an adjuvant treatment for 6 weeks.

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