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  1. Here, we test citicoline effectiveness as an adjuvant therapy in major depression. Method: A double-blind randomized trial was designed on 50 patients with major depressive disorder who were under treatment with citalopram.

  2. 7 Απρ 2018 · In head-to-head studies, agomelatine, amitriptyline, escitalopram, mirtazapine, paroxetine, venlafaxine, and vortioxetine were more effective than other antidepressants (range of ORs 1·19–1·96), whereas fluoxetine, fluvoxamine, reboxetine, and trazodone were the least efficacious drugs (0·51–0·84).

  3. 1 Ιαν 2017 · Research reports indicate that citicoline, in combination with citalopram, increased the effectiveness of SSRI drugs for depression and anxiety treatment (Roohi-Azizi et al., 2017; Nejati et al...

  4. 12 Φεβ 2021 · The recent systematic review and network meta-analysis of antidepressant clinical trials by Cipriani et al. provides the most comprehensive evidence base currently available to guide initial treatment choice and identifies three drugs as the preferred options: agomelatine, escitalopram and vortioxetine.

  5. 21 Απρ 2020 · All CPGs included serotonin selective reuptake inhibitors (SSRIs) as first-line treatment; however, one CPG also included agomelatine, milnacipran, and mianserin as first-line alternatives. Recommendations for depression subtypes (catatonic, atypical, melancholic) were included in three CPGs.

  6. These include drugs such as psychedelics, antibiotics, opioid modulators, neuropeptides, and onabotulinumtoxin. Neuromodulatory treatments such as light based therapies and neuromodulation involving either magnetic or electrical stimulation are also discussed.

  7. 2 Νοε 2021 · The study selected outpatients within 1 year from the stroke onset that had a diagnosis of PSD and were treated with either antidepressants or nootropic drugs (i.e. 1000 mg citicoline once daily orally for 6 months; 600 mg choline alphoscerate once daily orally for 6 months).

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