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  1. 29 Ιουλ 2024 · Many common medications affect thermoregulation, the process by which your body maintains a healthy temperature. Some of these medications, including antihistamines and diuretics, may make it difficult to stay cool on extremely hot days.

  2. 1 Μαΐ 2024 · A 2020 PLOS ONE study found that various commonly prescribed drugs interfere with the body’s ability to perceive and protect itself from heat, increasing the risk of hospitalization.

  3. The most commonly used drugs that affect thermoregulation include antipsychotic drugs, serotonergic drugs (especially when taken in combination), sympathomimetic drugs, anaesthetics and drugs with anticholinergic properties .

  4. 26 Ιουλ 2022 · Which medications may make heat more dangerous? Antidepressants like selective serotonin reuptake inhibitors, or SSRIs, may increase sweating, increasing the risk of dehydration. Others, like tricyclic antidepressants, or TCAs, may decrease sweating, making it harder to cool off.

  5. What is new and conclusion: Commonly used medicines that may significantly increase the risk include diuretics, especially when combined with an angiotensin converting enzyme (ACE) inhibitor or an angiotensin II receptor blocker (ARB), anticholinergics and psychotropics.

  6. Randomised studies exposing humans to exertional and/or passive heat stress that investigated a drug identified by WHO compared to no drug/placebo were eligible. The primary outcome was core temperature (e.g., rectal, oesophageal, aural, tympanic). We assessed risk of bias (Cochrane’s Risk of Bias 2) and certainty of evidence (GRADE).

  7. 13 Αυγ 2024 · Cardiovascular medicines, antipsychotics and other drugs have been linked to an increased risk of hospitalization during heat waves. But researchers don’t have a solid understanding of which ...