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  1. This document describes the U.S. Environmental Protection Agency‘s (EPA‘s) updated approach for evaluating the human health risks from exposures to environmental media containing dioxin-like compounds (DLCs). 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and DLCs are structurally and toxicologically related halogenated aromatic hydrocarbons.

  2. 20 Φεβ 2024 · EPA will use TEQs to account for how dioxin and dioxin-like compounds vary in toxicity. TEQs will help the public to better understand the toxicity of releases and waste management at facilities that report under the Toxics Release Inventory Program.

  3. An alternative approach which uses existing literature data and analytical results to calculate the “2,3,7,8-TCDD equivalent” concentration of a mixture in order to “predict” its biological potency relative to 2,3,7,8-TCDD itself is advanced here.

  4. Toxic equivalency factor (TEF) expresses the toxicity of dioxins, furans and PCBs in terms of the most toxic form of dioxin, 2,3,7,8-TCDD. [1] The toxicity of the individual congeners may vary by orders of magnitude.

  5. The “Toxic Equivalent” (TEQ) scheme weighs the toxicity of the less toxic compounds as fractions of the toxicity of the most toxic TCDD. Each compound is attributed a specific “Toxic Equivalency Factor” (TEF). This factor indicates the degree of toxicity compared to 2,3,7,8-TCDD, which is given a reference value of 1.

  6. 1 Ιαν 1987 · Toxic equivalency factors (TEFs), which relate the potency of individual polychlorinated dibenzo-p-dioxin (PCDD), dibenzofuran (PCDF), and biphenyl (PCB) congeners to 2,3,7,8-...

  7. 1 Ιαν 2023 · As a notorious compound in the family of dioxins, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exhibits long-term toxic effects on diverse organs, which induces continuous metabolic disorders. This review discussed the mechanisms of TCDD-associated metabolic syndrome.

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    2 3/7 as an improper fraction
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