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  1. A study by Schoenfeld et al. from 2022, conducted on five patients with Ledderhose’s disease and/or Dupuytren (four with plantar and two with both) treated with an oral multitargeted receptor tyrosine kinase inhibitor called Sorafenib, showed great results. The patients, who had been previously checked by surgeons, were inoperable due to the ...

  2. DD is a chronic disease for which there is no cure. Various treatments are available. Methods. This review is based on pertinent publications retrieved by a selective search in PubMed and Embase. Results. Genetic factors account for 80% of the factors involved in causing this disease.

  3. A systematic review of non-surgical treatments for early-stage Dupuytren’s disease identified various pharmacological treatments (oral, intramuscular, topical or intralesional steroids; vitamin E, furazolidone, aminosyn (an amino acid solution), hyperbaric oxygen), radiotherapy and physical therapies (ultrasound, splinting, frictional massage ...

  4. 27 Ιαν 2022 · Operative treatments include percutaneous needle fasciotomy (PNF), open fasciotomy (OF), Clostridium collagenase histolyticum (CCH) injections, limited fasciectomy (LF) and dermofasciectomy (DF). The various methods of DD treatment are reviewed. Results: We summarize the highlights of each treatment option as well as the strengths and weaknesses.

  5. Ledderhose disease, sometimes called Plantar Fibromatosis or ‘Dupuytren’s of the foot’, is characterised by lumps called nodules on the underside of the foot. These are caused by a thickening in the deep connective tissue (the fascia) in the foot and can cause discomfort or pain when walking.

  6. 28 Σεπ 2023 · Treatment involves removing or breaking apart the cords that are pulling your fingers toward your palm. This can be done in several ways. The choice of procedure depends on the severity of your symptoms and other health problems you may have.

  7. 14 Ιουλ 2023 · Dupuytren's contracture is an inherited disease of progressive fibrous tissue contracture of the palmar fascia. Predominantly affects men of northern European descent aged >40 years old who smoke, drink alcohol, or have diabetes. Patients present with a small lump or multiple lumps with pits in t...

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