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  1. 27 Ιαν 2022 · Question: What are the treatment options for Dupuytren's disease? Findings: Percutaneous needle fasciotomy has an immediate improvement but a higher recurrence rate and rare tendon, or nerve complications.

  2. 17 Σεπ 2023 · As some new treatments have offered a less-invasive way to manage Dupuytren's contracture, there are some healthcare providers who now recommend early treatment. With collagenase injections and needle aponeurotomy, repeat treatment is not as much of a concern.

  3. 3 Μαΐ 2022 · Researchers at the Kennedy Institute, University of Oxford, led by Professor Jagdeep Nanchahal have demonstrated the efficacy of the anti-TNF drug adalimumab for patients with early stage Dupuytren’s disease.

  4. A systematic review of non-surgical treatments for early-stage Dupuytren’s disease identified various pharmacological treatments (oral, intramuscular, topical or intralesional steroids; vitamin E, furazolidone, aminosyn (an amino acid solution), hyperbaric oxygen), radiotherapy and physical therapies (ultrasound, splinting, frictional massage ...

  5. 1 ημέρα πριν · Contractures in the fingers caused by Dupuytren disease are commonly treated with either limited fasciectomy or injection of collagenase. Evidence to guide the choice of treatment is limited, but ...

  6. Percutaneous needle fasciotomy is the least invasive method, with more rapid recovery and a lower complication rate than with limited fasciectomy. 85% of patients have a recurrence after an average of 2.3 years.

  7. Treatment for Dupuytren disease was first de-scribed by Henry Cline in the late 17th century and involved sectioning the pathologic cords, later known as fasciotomy or aponeurotomy.4 Since then, surgical intervention traditionally has been the most effective and widely accepted treatment for progressive Dupuytren contractures.1,2 Today’s