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16 Ιουν 2023 · Ionizing radiation is known to be DNA damaging and mutagenic, however less is known about which mutational footprints result from exposures of human cells to different types of radiation.
A series of reports from the U.N. Scientific Committee on the Effects of Atomic Radiation (UNSCEAR) has also addressed the genetic effects of radiation exposure on populations. Ionizing radiation damages the genetic material in reproductive cells and results in mutations that are transmitted from generation to generation.
As radiation kills cells by inhibiting their ability to divide, its effects in human beings occur primarily in tissues with high cell turnover or renewal rates characterized by a large amount of proliferative activity. These include tissues such as the bone marrow and the mucosal lining of the stomach and small intestine.
The possible effects of irradiating the stem cell niches in patients with glioma have generated considerable discussion, with the possibility of generating neurocognitive defects being placed against the chances of the niche being the source of glioma stem cells, suggesting that increased radiation dose to the subventricular zone may be ...
5 Απρ 2023 · This chapter describes the deleterious effects of radiation in humans causing cancer and genetic defects that result from DNA and chromosome damage by radiation. A brief description of cell structure and cell growth is given. Sources of radiation exposure to the US population are given.
19 Ιουν 2017 · Haploidy results in major differences in cell size and gene expression levels while also affecting parental imprinting, X chromosome inactivation, and mitochondrial metabolism genes. We discuss here haploidy in evolution and the barriers to haploidy, in particular in the human context. Previous. Next. Haploid. Ploidy. Human. Embryonic stem cells.
19 Ιουν 2017 · Haploidy results in major differences in cell size and gene expression levels while also affecting parental imprinting, X chromosome inactivation, and mitochondrial metabolism genes. We discuss here haploidy in evolution and the barriers to haploidy, in particular in the human context.
