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Potential mechanisms for smoke's harmful effects include oxidative stress, inflammation, and atherosclerotic processes. Recent evidence implicates medicinal nicotine as potentially harmful to both neurodevelopment in children and to catalyzing processes underlying neuropathology in Alzheimer's Disease.
10 Αυγ 2022 · Together, this emerging evidence from both preclinical and clinical studies underscores the neurotoxic effects of nicotine exposure during sensitive periods of brain development and highlights the ability of nicotine to pathologically interfere with a host of neurochemical, morphological, and molecular pathways critical to healthy cognitive ...
10 Αυγ 2007 · Smoking is associated with an increased incidence of cardiovascular disease including coronary heart disease (e.g., angina, myocardial infarction, sudden-death, and congestive heart failure), cerebrovascular disease (e.g., transient ischemic attacks, stroke), and vascular diseases (e.g., claudication, aortic aneurysm and atherosclerosis) and is ...
1 Μαρ 2020 · Nevertheless, in vitro and in vivo preclinical studies strongly indicate that nicotine exposure alone can adversely affect the nervous, respiratory, immune, and cardiovascular systems, particularly when exposure occurs during critical developmental periods.
6 Ιουλ 2021 · Tobacco smoking shows a strong association with other cardiovascular diseases like coronary artery disease, heart failure, and atrial fibrosis. A recent meta-analysis has shown that smoking only one cigarette per day carries 50% of the risk of developing coronary artery disease as smoking 20 cigarettes per day [ 48 ].
16 Ιουν 2021 · Tobacco has a significant negative impact on the development of nervous structures, neurotransmission and cognitive functions, and promotes the development of neurodegenerative diseases, insomnia and cerebrovascular diseases.
24 Μαρ 2022 · Neurobiological findings have identified the mechanisms by which nicotine in tobacco affects the brain reward system and causes addiction.
