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  1. Abstract. Nicotine dependence is associated with increased risk for emotional, cognitive, and neurological impairments later in life. This study investigated the long-term effects of nicotine exposure during adolescence and adulthood on measures of depression, anxiety, learning, and hippocampal pyramidal cell morphology.

  2. In this paper, we review recent literature, laboratory and epidemiologic, that describes the components of mainstream and sidestream tobacco smoke, including heavy metals and their toxicity, the effect of medicinal nicotine on the brain, and studies of the relationship between smoking and (1) preclinical brain changes including silent brain ...

  3. 8 Ιουν 2022 · Loss of nAChRs has been reported to lead to impairment of cognition and social behavior (Nacer et al., 2021) and nicotine mediates the effects of water pipe tobacco smoking (WTS) on resilience to stress by increasing brain-derived neurotrophic factor (BDNF) and tropomyosin receptor kinase B (TRKB) levels and signaling.

  4. 10 Αυγ 2007 · Potential mechanisms for smoke’s harmful effects include oxidative stress, inflammation, and atherosclerotic processes. Recent evidence implicates medicinal nicotine as potentially harmful to both neurodevelopment in children and to catalyzing processes underlying neuropathology in Alzheimer’s Disease.

  5. 1 Μαρ 2023 · The current review will extend previous narrative work by systematically reviewing all human and animal evidence for age differences in the effects of tobacco smoke and nicotine on cognition and the brain, with a focus on the effects of repeated and long-term exposure.

  6. 30 Ιουν 2021 · Smokers were intact on processing speed. Smoking accumulation and lower age onset of regular smoking were correlated with lower neuropsychological function. Our findings add to the growing body of evidence suggesting that chronic tobacco smoking impacts cognition negatively.

  7. 24 Μαρ 2022 · Neurobiological findings have identified the mechanisms by which nicotine in tobacco affects the brain reward system and causes addiction. These brain changes contribute to the maintenance of...

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