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Severity of hypercalcaemia. <3.0 mmol/L: often asymptomatic and does not usually require urgent correction 3.0–3.5 mmol/L: may be well tolerated if it has risen slowly, but may be symptomatic and prompt treatment is usually indicated. > mmol/L: requires urgent correction due to the risk of dysrhythmia and coma.
Pancreatitis. Peptic ulceration. Hypertension, cardiomyopathy. Muscle weakness. Band keratopathy. Causes. Ninety percent of hypercalcaemia is due to primary hyperparathyroidism or malignancy. Less common causes include. Thiazide diuretics.
8 Μαρ 2024 · Very high calcium levels can be a medical emergency. You might need treatment with IV fluids in the hospital to quickly lower your calcium level. This helps prevent heart rhythm problems or damage to the nervous system.
7 Μαΐ 2024 · Identify signs and symptoms of hypercalcemia. Interpret laboratory and imaging results accurately to determine the underlying cause of hypercalcemia. Evaluate differentials to determine the etiology of hypercalcemia. Determine appropriate treatment options for hypercalcemia.
8 Μαρ 2024 · Treatment for hypercalcemia should be aimed both at lowering the serum calcium concentration and, if possible, treating the underlying disease. Effective treatments reduce serum calcium by inhibiting bone resorption, increasing urinary calcium excretion, or decreasing intestinal calcium absorption . The optimal choice varies with the cause and ...
2 Ιουν 2015 · Treatment with a calcimimetic agent, cinacalcet, is an option in selected cases. Severe hypercalcaemia requires admission to hospital and treatment with aggressive intravenous hydration and bisphosphonates along with treatment of the underlying disease.
The foundation of hypercalcemia treatment is isotonic saline hydration. This corrects the volume depletion caused by hypercalcemia-induced diabetes insipidus and concomitant nausea and vomiting. Saline infusion of three to six liters over 24–48 hours can lower calcium levels by 1–3 mg/dL.