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Evidence of a disordered ENS has accumulated in neurodegenerative diseases ranging from amyotrophic lateral sclerosis, Alzheimer disease and multiple sclerosis to Parkinson disease as well as neurodevelopmental disorders such as autism.
29 Ιαν 2021 · Evidence of a disordered ENS has accumulated in neurodegenerative diseases ranging from amyotrophic lateral sclerosis, Alzheimer disease and multiple sclerosis to Parkinson disease as well as...
8 Αυγ 2018 · This review presents the latest evidence for ENS involvement in two common neurodegenerative disorders, Parkinson’s disease (PD) and Alzheimer’s disease (AD), and discusses the need for sampling the ENS for disease monitoring and therapeutic development.
20 Ιουλ 2016 · The enteric nervous system (ENS) is large, complex and uniquely able to orchestrate gastrointestinal behaviour independently of the central nervous system (CNS). An intact ENS is essential...
15 Σεπ 2016 · Enteric neurons arise from neural crest cells and regulate gastrointestinal function. Congenital neurointestinal diseases result from abnormal development of enteric neurons. Acquired neurointestinal diseases result from neuronal degeneration, inflammation, or infection.
The enteric nervous system (ENS) is large, complex and uniquely able to orchestrate gastrointestinal behaviour independently of the central nervous system (CNS). An intact ENS is essential for life and ENS dysfunction is often linked to digestive disorders.
Our results indicate a remarkable rate of turnover of adult neurons in the small intestine and provide a unique paradigm for understanding the ENS in health and disease. Significant Neuronal Loss Occurs in the ENS in the Healthy Adult Gut.
