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Baseline progesterone levels are often useful in mares with a history of early embryonic loss. For mares confirmed pregnant early in gestation and not pregnant later, PMSG and/or estrone sulfate may be useful in determining whether or not placentation was established.
The inversion of the ratio of progesterone:DHP provides objective evidence that placental viability and development are sufficient for pregnancy maintenance and may be valuable in confirming that exogenous progestin therapies like altrenogest are no longer needed.
26 Ιουν 2023 · Any mare that has a history of repeated pregnancy loss, serum progesterone levels of 4 ng/mL or less, or mares demonstrating uterine edema on transrectal ultrasonography, should be started on exogenous progesterone. Products include oral altrenogest administered at a dose of 0.044 mg/kg given daily. Most mares tolerate this well.
1 Ιουλ 2016 · Systemic plasma concentrations of 17OH-progesterone and androstenedione measured weekly during equine pregnancy graphed alongside estrone sulfate measured daily until Day 60 of gestation.
7 Ιουλ 2016 · In summary, current tests for progesterone in the mare are useful to evaluate the presence of luteal tissue (P4>1ng/mL) and to ensure that levels of circulating progesterone are adequate for maintenance of early pregnancy (P4>4ng/mL) until about 120 days of gestation.
8 Ιουλ 2016 · During early pregnancy, progesterone is produced in the equine ovary by the corpus luteum (CL), and its concentrations remain elevated and peak between 60 and 120 days of gestation. From that...
23 Ιουν 2020 · Utilised to suppress oestrous, delay ovulation, maintain pregnancy, and for behavioural modifications, progestins are a commonly administered class of pharmaceuticals in veterinary medicine. In this review, we discuss the progestins available to equine industry, in addition to assessing efficacy, pharmacokinetics, and potential side effects ...