Αποτελέσματα Αναζήτησης
3 Ιουν 2011 · There are two types of somatic gene therapy: Ex vivo – the new gene is inserted via a virus vector into the cell outside the body. Blood or bone marrow cells are extracted and exposed to the virus which inserts the gene into these cells. These cells are then grown in the laboratory and returned to the person by an injection into a vein
For example, genes that encode proteins capable of breaking down mycotoxins (Karlovsky, 2011) or inhibiting the activity of cell-wall-degrading enzymes can be introduced into plants. Plants can be engineered to synthesize and secrete antimicrobial peptides or compounds that directly inhibit colonization ( Osusky et al., 2000 ).
With the emergence of new CRISPR-based tools, targeted gene editing has become increasingly efficient and flexible in plant cells. In addition to targeted gene mutagenesis, other types of genetic modifications, such as base substitution, gene knock-in and replacement, have become achievable in multiple plant species (Tables 1 and 2). New ...
This chapter provides a brief description of genetic modification methods used to develop new plant, animal, and microbial strains for use as human food. The next chapter (Chapter 3) presents a detailed analysis of the likelihood for these methods to result in unintentional compositional changes.
1 Αυγ 1999 · It has been successfully applied in the gene therapy of some single gene genopathy and plant genetical modification. The principle, examples and prospect of this technique was described.
10 Μαρ 2023 · Main approaches used to create stable transgenic plants include (i) biolistic bombardment of plant cells and tissues with DNA coated nanoparticles using a gene gun, and (ii) Agrobacterium mediated transformation.
When delivered into plant cells, SSN locate and cleave the target DNA, resulting in double-strand breaks (DSBs) that are repaired by natural DNA repair mechanisms like non-homologous end-joining (NHEJ) and homology-directed repair (HDR).
