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Inversions are structural mutations that reverse the sequence of a chromosome segment and reduce the effective rate of recombination in the heterozygous state. They play a major role in adaptation, as well as in other evolutionary processes such as speciation.
25 Ιαν 2019 · Early studies of inversions were restricted to species with easily visualised chromosomes (e.g., flies). Today, inferring the presence of inversions is technically possible in many species as reference genomes, genetic maps, and extensive sequencing data become available.
28 Σεπ 2010 · Inversions are a diverse class of chromsomal mutation. The majority are small (<1KB) [3]. Others, for example the famous 3RP inversion of Drosophila melanogaster, are several megabases in size, include several percent of the entire genome and span hundreds or thousands of genes [10].
17 Οκτ 2022 · Examples of inversion breakpoints near large inverted repeats (inv9.0, inv15.2, inv20.0) and segmental duplications (inv9.0, inv15.2, inv20.0, inv18.0).
28 Σεπ 2010 · A clear sign that inversions are involved in adaptation comes from geographical variation in their frequency. A dramatic example is the inversion 3RP in Drosophila melanogaster, which has established parallel latitudinal clines on three continents .
17 Σεπ 2019 · Actually, inversions have been a model in evolutionary biology for almost 90 years 30,31 and there are numerous examples of their phenotypic consequences and adaptive significance in diverse...
14 Νοε 2023 · Inversions, a type of chromosomal structural variation, significantly influence plant adaptation and gene functions by impacting gene expression and recombination rates. However, compared with other structural variations, their roles in functional biology and crop improvement remain largely unexplored.
