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Some affected individuals have few or no symptoms while others may experience life-threatening bleeding. Typically this bleeding disorder manifests itself as a tendency to easy bruising, nose bleeding, heavy and prolonged menstruation, and excessive bleeding after dental or surgical interventions.
People with severe FVII deficiency experience joint and muscle bleeds, easy bruising and bleeds after surgery. Bleeds can also occur in the skin, mouth, nose and genitourinary tract. Women often experience severe menorrhagia, long, heavy periods.
28 Μαΐ 2023 · The symptoms of factor VII deficiency can vary depending on the severity of the disease. These are its common symptoms: Frequent bruising Bleeding in soft tissues and muscles
Factor VII deficiency is the most common among rare inherited autosomal recessive bleeding disorders, and is a chameleon disease due to the lack of a direct correlation between plasma levels of coagulation Factor VII and bleeding manifestations.
People who do not have this bleeding disorder will have a FVII level of greater than 50% on a laboratory test. People affected with FVII Deficiency have less than 50% FVII circulating in their blood stream. 1 Your doctor can tell you what your FVII level is. Factor VII Deficiency affects approximately 1 in 500,000 individuals.2 It is also
9 Μαΐ 2023 · Factor VII deficiency is a rare genetic bleeding disorder characterized by a deficiency or reduced activity of clotting factor VII. Clotting factors are specialized proteins that are essential for the blood to clot normally. Individuals with factor VII deficiency can experience prolonged, uncontrolled bleeding episodes.