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5 ημέρες πριν · Febrile neutropenia is the presence of fever in a neutropenic patient. It is the most common life-threatening complication of cancer therapy and is considered an oncologic emergency.
- Febrile Neutropenia
Febrile neutropenia is the most common life-threatening...
- Febrile Neutropenia
30 Μαρ 2023 · Febrile neutropenia is the most common serious and common complication of cancer therapy. This activity reviews the management and highlights the tools needed by an interprofessional team to evaluate patients with febrile neutropenia properly.
Neutropenia: Presence of absolute neutrophil count <0.5 X 10 9/L, or <1,0 X 10 /L predicted to fall below 0.5 X 109/L within 48 h. The lower the neutrophil count, the greater the risk of infection
What clinical features and laboratory markers can be used to classify pediatric patients with FN as being at low-risk or high-risk for poor outcomes? What clinical, laboratory and imaging studies are useful at the initial presentation of FN to assess the etiology of the episode and guide future treatment?
Laboratory tests, including complete blood cell counts with differential leukocyte and platelet counts, are needed to determine ANC and severity of neutropenia.
Febrile neutropaenia (FN) is defined as an oral temperature of >38.3°C or two consecutive readings of >38.0°C for 2 h and an absolute neutrophil count (ANC) of <0.5 × 10 9 /l, or expected to fall below 0.5 × 10 9 /l.
If unwell, ask for senior review Fever ≥ 38 °C And Neutrophils ≤ 0.5 (Consider starting antibiotics if neutrophil count ≥ 0.5 but falling counts or if other risk factors (e.g. mucositis, Down Syndrome or stem cell transplant.)