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27 Απρ 2020 · A high intake of linoleic acid (LA), the major dietary polyunsaturated fatty acid (PUFA), has previously been associated with reduced cardiovascular (CV) morbidity and mortality in...
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Download PDF. Linoleic acid (18:2ω6; cis, cis-9,12-octadecadienoic acid) is the most highly consumed PUFA found in the human diet. On consumption, linoleic acid has 4 primary fates. Like all fatty acids, it can be used as a source of energy.
13 Ιουλ 2023 · The intake of linoleic acid (LA) has increased dramatically in the standard American diet. LA is generally promoted as supporting human health, but there exists controversy regarding whether the amount of LA currently consumed in the standard American diet supports human health.
10 Ιουν 2011 · Decreasing dietary linoleic acid by up to 90% was not significantly correlated with changes in arachidonic acid levels in the phospholipid pool of plasma/serum (p = 0.39).
6 Ιαν 2016 · linoleic acid for 24 months is well tolerated by and reduces body fat mass in healthy, overweight humans.
10 Ιουν 2011 · The concern with dietary linoleic acid, being the metabolic precursor of arachidonic acid, is its consumption may enrich tissues with arachidonic acid and contribute to chronic and overproduction of bioactive eicosanoids.
Between 1959 and 2008—a period associated with the ongoing diabetes and obesity epidemic—linoleic acid levels in adipose tissue in US adults increased by 136% (from 9·1% to 21·5%).4 This increase correlates (r2=0·81) with increased dietary intake of linoleic acid, as measured by the United States Department of Agriculture Economic Research Servi...
