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Specific thresholds for ferritin are used to detect iron deficiency and overload in different age groups. The World Health Organization (WHO) estimates that 42% of children less than 5 years of age and 40% of pregnant women worldwide are anaemic.
21 Απρ 2020 · This guideline provides global, evidence-informed recommendations on the use of indicators for assessing a population’s iron status and application of the use of ferritin concentrations for monitoring and evaluating iron interventions.
Elevated ferritin levels, when all other iron markers (such as serum iron, total iron-binding capacity (TIBC), and transferrin saturation) are normal, can indicate several possible conditions. Ferritin is a protein that stores iron, and its levels can be influenced by factors other than iron status.
The most commonly used thresholds of serum ferritin concentration to diagnose iron deficiency in studies of iron and/or micronutrient supplementation in pregnant women were <12 μg/L (35 studies) and <15 μg/L (17 studies).
In addition, individuals with infection (white blood cell counts >10·0 × 10 9 /L) and non-pregnant women with possible liver disease (ALT >70 IU/L or AST >70 IU/L) 16 and inflammation (CRP >5·0 mg/L). 17 The WHO cutoff for severe risk of iron overload is a serum ferritin concentration of more than 150 μg/L for women and girls older than 5 ...
11 Οκτ 2021 · The World Health Organization (WHO) recently recommended ferritin thresholds of less than 15 μg/L (adults) and less than 12 μg/L (children) for the diagnosis of iron deficiency, but these thresholds were based largely on expert opinion along with historical studies correlated with absence of bone marrow iron stores. 1,2
2 Νοε 2023 · Over the age of 50, the lower limit of the ferritin reference ranges for women increased, approaching but not equaling or exceeding the values observed for men until ages greater than 70. This may reflect the end of menses and the gradual repletion of iron stores.
