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Fibrosing mediastinitis (FM), which is also known as mediastinal fibrosis or sclerosing mediastinitis, is an uncommon, benign and progressive condition characterized by an invasive proliferation of fibrous tissue within the mediastinum.
Fibrosingmediastinitis (FM), also known as collagenosis or sclerosing mediastinitis, is a rare but fatal disease with few therapeutic options. The causes of FM include mediastinal exposure to the Histoplasma capsulatum antigen, which induces an intense inflammatory response, resulting in proliferation and invasion of fibrous tissue into vital ...
12 Δεκ 2016 · In this expert consensus, the evidence for strategies for treatment and prevention of mediatinitis is reviewed in detail aiming at reducing the incidence and optimizing the management of this serious condition.
Management of fibrosing mediastinitis. Specialists at Mayo Clinic have used off-label rituximab to treat nearly 30 patients with fibrosing mediastinitis successfully. Disease progression was almost universally halted and two-thirds of the patients improved symptomatically.
12 Μαΐ 2018 · Although rare, fibrosing mediastinitis is an insidious complication of pulmonary histoplasmosis that must be recognized quickly, along with rapid stabilization and carefully crafted treatment plan. Medical therapy with antifungals and corticosteroids is not recommended routinely.
14 Δεκ 2019 · In patients with significant vascular occlusion with hemodynamic compromise, both stenting and surgical intervention (bypassing the occlusion) may be required to treat the vascular occlusion. Endovascular therapy is a safe and feasible treatment option with an acceptable safety profile with a high level of technical success .
15 Ιουλ 2014 · Diagnosis can be made rapidly by serological tests, staining, and culture of bronchoalveolar lavage fluid and, in rare cases, biopsy. Therapy with antifungal drugs can result in marked improvement of symptoms. 1 Fibrosing mediastinitis is a rare complication of histoplasmosis. Dissemination of fungal antigens in the pulmonary reticulo ...
