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Fibrosing mediastinitis (FM), which is also known as mediastinal fibrosis or sclerosing mediastinitis, is an uncommon, benign and progressive condition characterized by an invasive proliferation of fibrous tissue within the mediastinum.
Management of fibrosing mediastinitis. Specialists at Mayo Clinic have used off-label rituximab to treat nearly 30 patients with fibrosing mediastinitis successfully. Disease progression was almost universally halted and two-thirds of the patients improved symptomatically.
20 Αυγ 2021 · Medical treatments can help address some of the symptoms and complications caused by fibrosing mediastinitis. When fluid retention occurs related to vascular obstructions, patients are treated with diuretic therapy. Antibiotics can be used to treat complications such as pneumonia.
The rampant mediastinal fibrosis has been ascribed to chronic inflammation in response to various antigens. The extent of the initial clinical symptoms and their relationship to the compromise of specific mediastinal structures should guide the therapeutic approach [1].
Fibrosing mediastinitis (FM) is a rare disorder characterized by the invasive proliferation of fibrous tissue within the mediastinum. FM frequently results in the compression of vital mediastinal structures and has been associated with substantial morbidity and mortality.
14 Δεκ 2019 · Here, we present two cases of young patients with fibrosing mediastinitis complicated by pulmonary artery stenosis requiring medical and endovascular management with excellent results.
15 Ιουλ 2014 · Diagnosis can be made rapidly by serological tests, staining, and culture of bronchoalveolar lavage fluid and, in rare cases, biopsy. Therapy with antifungal drugs can result in marked improvement of symptoms. 1 Fibrosing mediastinitis is a rare complication of histoplasmosis.
