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Follicular atresia is a normal process in the ovary (Figure 26.6) to regulate the number of follicles in the developing pool and increases in follicular atresia can be observed secondary to xenobiotic administration.
Exhaustion of the follicular reserve occurs at menopause, which is typically around the age of 51 in humans with ovaries. The dramatic decrease in estrogen and progesterone levels that is characteristic of menopause is caused by follicular atresia.
Follicle atresia is an event that happens in all stages of follicles. It is essential for maintaining ovular environmental homeostasis and the abnormity of follicle atresia causes reproductive diseases such as the polycystic ovarian syndrome and premature ovarian failure [4,5].
Defective autophagy in the follicular cells during different stages of follicles is observed in the PCOS ovary. Exploring different autophagy pathways provides a platform for predicting the possible cause of altered ovarian physiology in PCOS.
20 Φεβ 2023 · Follicular atresia triggered by granulosa cell (GC) apoptosis severely reduces female fertility and accelerates reproductive aging. GC apoptosis is a complex process regulated by multiple...
Ovary follicle atresia refers to a complex hormonally driven process in the mammalian ovary that involves the degeneration and loss of ovarian follicles. AI generated definition based on: Knobil and Neill's Physiology of Reproduction (Fourth Edition) , 2015
