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In this review, we summarize the impact and the relationships between sympathovagal disturbances and kidney diseases, replacement therapies and transplantation. Kidney diseases are associated with many cardiovascular risk factors, such as anaemia, inflammation and chronic volume overload.
The kidneys play a central role in cardiovascular homeostasis by ensuring a balance between the fluid taken in and that lost and excreted during everyday activities. This ensures stability of extracellular fluid volume and maintenance of normal levels of blood pressure.
1 Ιαν 2013 · By contrast, short-term dynamic control in response to changes in sodium and water intake and loss through normal everyday activities are primarily determined by the direct actions of the autonomic nervous system, via the renal sympathetic nerves, and indirectly via the renin–angiotensin system.
14 Ιουν 2015 · Cardiovascular autonomic dysfunction is a major complication of chronic kidney disease (CKD), likely contributing to the high incidence of cardiovascular mortality in this patient population.
19 Φεβ 2021 · The present paper will review the impact of the therapeutic approaches employed in the management of renal failure on the autonomic dysfunction characterizing the disease. This will be done first by discussing the autonomic effects of cardiovascular drugs in patients with renal failure.
12 Δεκ 2016 · At the level of the kidney, the renal nerves play a critical role in regulation of renal function from filtration to control of the renin angiotensin system (RAS), with central processing integral to these functions.
Under physiological states, the nervous system and the kidneys communicate with each other to maintain normal body homeostasis. However, pathological states disrupt this interaction as seen in hypertension, and kidney damage can cause impaired renorenal reflex and sodium handling.
