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  1. 24 Αυγ 2020 · Although data on the concentration of nickel in blood [13–18], urine [13–16, 19–22] or hair [14–16] can be found among recently published literature, only a few publications regarding nickel content in human internal organs are available.

  2. 18 Φεβ 2020 · Nickel enzymes, present in archaea, bacteria, plants, and primitive eukaryotes are divided into redox and nonredox enzymes and play key functions in diverse metabolic processes, such as energy metabolism and virulence.

  3. 24 Αυγ 2020 · That is why it is of a great importance to establish “reference” levels of particular elements (essential or toxic) in human biological samples. The aim of this paper was to determine nickel in autopsy tissues of non-occupationally exposed subjects in Southern Poland (n = 60).

  4. It has been proven that contact with nickel compounds (both soluble and insoluble) can lead to many pathological effects [2, 4], among which allergy in the form of contact dermatitis (estimated in 1020% of the general population) –. is the most common and known reaction of the human body to nickel [2, 5, 6].

  5. 11 Δεκ 2020 · Monovalent, divalent, and trivalent forms of nickel occur in living organisms. In a tightly bound form, the divalent form (Ni 2+) is required for the activity of urease, an enzyme found in plants and micro-organisms. Trivalent nickel is used for enzymatic hydrogenation, desulfurization, and carboxylation reactions in anaerobic micro-organisms.

  6. 15 Απρ 2021 · Nickel can affect the secretion of GH and IGF-1 in the growth hormone axis, further affecting the growth and development of the human body. At the same time, nickel can act on the target organs of growth hormone, induce liver apoptosis, produce oxidative stress and lead to liver injury.

  7. Nickel is also an micronutritient essential for proper functioning of the human body, as it increases hormonal activity and is involved in lipid metabolism. This metal makes it's way to the human body through respiratory tract, digestive system and skin.

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