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Furosemide is prepared from 4,6-dichlorobenzoic acid-3-sulfonylchloride via a multistep synthesis involving the sequential addition of ammonia and 6-furfurylamine (Sturm et al., 1962). It is synthesized in Brazil, Bulgaria, China, Hungary, Israel, Italy, Poland, Switzerland and the USA (Chemical Information Services, 1989–90).
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Η φουροσεμίδη είναι ένα διουρητικό της αγκύλης που δημιουργεί μια συγκριτικά ισχυρή και βραχείας διάρκειας διούρηση με ταχεία έναρξη. Η διουρητική δράση επιτυγχάνεται με αναστολή της ...
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The volume of distribution following intravenous administration of 40 mg furosemide were 0.181 L/kg in healthy subjects and 0.140 L/kg in patients with heart failure. 6 Protein binding Plasma concentrations ranging from 1 to 400 mcg/mL are about 91-99% bound in healthy individuals.
6 Απρ 2024 · Furosemide, a potent loop diuretic widely used for managing fluid overload conditions like congestive heart failure, liver cirrhosis, and renal dysfunction, is thoroughly reviewed in this paper.
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