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Gene activation is the process by which a gene is turned on and begins to produce its corresponding RNA and protein products. This process is essential for cellular functions and development, as it allows cells to respond to environmental signals and changes, influencing cell behavior and identity.
- Vocab, Definition, and Must Know Facts
Definition. Gene activation is the process by which a gene's...
- Vocab, Definition, and Must Know Facts
3 Μαρ 2021 · Gene activation The process of activation of a gene so that it is expressed at a particular time. This process is crucial in growth and development.
Transcriptional activators are required to turn on the expression of genes in a eukaryotic cell. Activators bound to the enhancer can facilitate either the recruitment of RNA polymerase II to the promoter or its elongation. This article examines a few selected issues in understanding activator functions and activation mechanisms.
In the previous section, we described the basic components of genetic switches—gene regulatory proteins and the specific DNA sequences that these proteins recognize. We shall now discuss how these components operate to turn genes on and off in response to a variety of signals.
Definition. Gene activation is the process by which a gene's expression is initiated, leading to the production of RNA and ultimately proteins. This process is critical for regulating biological functions, allowing cells to respond to environmental cues and developmental signals.
1 Ιαν 2014 · In contrast, the roles of ncRNAs in activating gene expression remains poorly understood. In this review, we summarize the current knowledge of gene activation by small RNAs, long non-coding RNAs, and enhancer-derived RNAs, with an emphasis on epigenetic mechanisms.
Further examples of AP-1 bound activation hubs are observed at key macrophage regulatory genes including MAFB and IL1β (Fig. S6A–C). The gain of AP-1 enhancer-promoter interactions are in certain cases marked as well by CTCF binding, suggesting AP-1 binding may be directed towards gene promoters for gene activation by CTCF .
