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How different genes are expressed in different cell types. The big picture of eukaryotic gene regulation.
The lac operon of E. coli contains genes involved in lactose metabolism. It's expressed only when lactose is present and glucose is absent. Two regulators turn the operon "on" and "off" in response to lactose and glucose levels: the lac repressor and catabolite activator protein (CAP).
20 Δεκ 2023 · Some examples of direct gene activation include the activation of genes involved in immune response when the body encounters a pathogen, the activation of genes involved in muscle growth during exercise, and the activation of genes involved in cell repair after an injury.
Gene activation refers to the process where genes are turned on in response to changes in neural activity, leading to the expression of specific genes in the brain. This activation can be observed in both birds and humans through various methods such as motor- and sensory-driven gene expression and imaging techniques like PET and MRI.
As stated above, gene expression in prokaryotes is regulated at the level of transcription, whereas in eukaryotes, gene expression is regulated at multiple levels, including the epigenetic (DNA), transcriptional, pre- and post-transcriptional, and translational levels.
Gene activation occurs when a stimulation, normally a physical-biological element, stimulates the natural proteins that are part of the genetic material of cells and is thus turning the genes “on” that were “off” and is therefore considered to be gene-regulating.
Gene activation is the process by which a gene is turned on and begins to produce its corresponding RNA and protein products. This process is essential for cellular functions and development, as it allows cells to respond to environmental signals and changes, influencing cell behavior and identity.