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Gene Activation. Gene activation (transactivation) is mediated by binding of the glucocorticoid-glucocorticoid receptor complex to a defined sequence in the promoter regions of the target genes, termed Glucocorticoid Responsive Elements (GRE) (Beato et al., 1989).
Transcriptional activators are required to turn on the expression of genes in a eukaryotic cell. Activators bound to the enhancer can facilitate either the recruitment of RNA polymerase II to the promoter or its elongation. This article examines a ...
Most gene regulatory proteins that activate gene transcription—that is, most gene activator proteins—have a modular design consisting of at least two distinct domains. One domain usually contains one of the structural motifs discussed previously that recognizes a specific regulatory DNA sequence.
Gene activation refers to the process where genes are turned on in response to changes in neural activity, leading to the expression of specific genes in the brain. This activation can be observed in both birds and humans through various methods such as motor- and sensory-driven gene expression and imaging techniques like PET and MRI.
Gene Activation. In subject area: Immunology and Microbiology. ZGA stands for zygotic genome activation or zygotic gene activation, in which the paternally derived genome and maternally derived genome are transcribed for the first time after fertilization. From: Current Topics in Developmental Biology, 2016.
20 Δεκ 2023 · Gene activation refers to the process by which a gene is turned “on” or activated, meaning that the gene’s DNA is transcribed into RNA, and ultimately, translated into protein. This process is tightly regulated and involves a multitude of factors that work together in a highly orchestrated manner.
Direct Gene Activation. Receptors that can directly influence gene expression are termed nuclear receptors. Located within the cytosol or nucleus, nuclear receptors are the target of steroid and thyroid hormones that are able to pass through the cell membrane.
