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23 Σεπ 2021 · Despite the difficulties in validating causative mutations and variants, genetic studies into both rare and common obesity over the past two decades have revealed two surprisingly cogent ...
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14 Σεπ 2017 · Gene by environment and lifestyle interaction analyses have revealed that our increasingly obesogenic environment might be amplifying genetic risk for obesity, yet those at highest risk could mitigate this risk by increasing physical activity and possibly by avoiding specific dietary components.
25 Ιουν 2021 · Although lifestyle factors including inadequate dietary habits, decreased physical activity, and more prominently, an unhealthy body weight, may be partly responsible for this disproportion in chronic diseases, genetic variations also make a substantial contribution to this problem.
11 Οκτ 2023 · Enormous progress has been made in understanding the genetic architecture of obesity and the correlation of epigenetic marks with obesity and related traits. This review highlights current research and its challenges in genetics and epigenetics of obesity.
Abstract. There is a genetic component to human obesity that accounts for 40% to 50% of the variability in body weight status but that is lower among normal weight individuals (about 30%) and substantially higher in the subpopulation of individuals with obesity and severe obesity (about 60%-80%).
13 Μαΐ 2022 · For children with early onset obesity, genetic screening is recommended for those having clinical features of genetic obesity syndromes (including hyperphagia).
2 Ιουλ 2024 · As obesity is causally associated with multimorbidity, we further investigated the effect of adherence to a healthy lifestyle on the risks of 20 obesity-related morbidities (ORMs) using genetic, lifestyle, and comorbidity data from 338,645 individuals of European ancestry.
