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3 Φεβ 2023 · In this Review, we describe how the sequencing of genomes from modern and archaic hominins, great apes and other primates is revealing human-specific genetic changes and how new molecular and...
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DNA and its building blocks. DNA is made of four types of nucleotides, which are linked covalently into a polynucleotide chain (a DNA strand) with a sugar-phosphate backbone from which the bases (A, C, G, and T) extend. A DNA molecule is composed of two (more...)
Genetics and genetic engineering provide powerful tools for the study of gene function in both cells and organisms. In the classical genetic approach, random mutagenesis is coupled with screening to identify mutants that are deficient in a particular biological process.
Draw the structure of an ‘average’ human gene. Categorize the human gene catalog into different functional classes. Distinguish between conventional and processed pseudogenes and other types of evolutionary relic. Give specific examples of the repetitive DNA content of the human genome.
2 Ιαν 2021 · Systematic genetic mapping in families and populations helped scientists pinpoint the genetic variants that contribute to human disease. The effects have been profound.
1 Μαρ 2021 · With their see-through bodies, low maintenance costs and genetic similarity to humans, zebrafish provide a powerful animal model for studying mental disorders and metabolic diseases in the...
1 Μαρ 2005 · Here, we review the mechanistic relationship between human disease phenotypes and the function of the centrosome, and describe some of the newly-appreciated functions of this organelle in...
