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Once-daily dosing for gentamicin is recommended for most patients, except in endocarditis, where lower, multiple daily dosing is used. Once daily doses: The gentamicin dosing calculator on the GAPP app should be used to calculate the gentamicin dose.
3 Αυγ 2023 · Detailed Gentamicin dosage information for adults and children. Includes dosages for Bacterial Infection, Urinary Tract Infection, Skin or Soft Tissue Infection and more; plus renal, liver and dialysis adjustments.
An antimicrobial app and/or online calculator is available and should be used to calculate the initial gentamicin dose. STEP 1: . Calculate, prescribe and administer the first dose. To reduce the risk of mortality, commence gentamicin administration within 1 hour of recognising sepsis.
Calculate the initial dose by multiplying the patient’s actual body weight (or corrected dosing weight if the patient is obese) by 2.5 (i.e. 2.5 mg/kg ) to a maximum of 180 mg. Alternatively a SINGLE dose of 7 mg/kg may be considered (do not repeat this dose).
Calculating the first dose of gentamicin. If creatinine is known ‐ use the online gentamicin dose calculator. If creatinine is not known ‐ give 5mg/kg gentamicin (maximum 400 mg) or, if CKD 4 or 5, give 2∙5mg/kg (maximum 180mg) on advice of senior medical staff.
IV Injection (not suitable for once daily dosing) IV bolus over 3 - 5 minutes undiluted. IV Infusion. Add the total dose of gentamicin to 100mL of infusion fluid and administer over 20 minutes. Preferably administer via a central venous access device to avoid potential venous irritation.
Step 1: Calculate, prescribe and administer the first dose. To reduce the risk of mortality, commence gentamicin administration within 1 hour of recognising sepsis. If creatinine is known – use the online Gentamicin calculator (preferred method) or the guidelines in Table 1 (below).
