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18 Σεπ 2018 · There is no change in life expectancy due to Gilbert’s syndrome. However, if you start to notice symptoms, you may need to make some lifestyle changes. How we reviewed this article:
5 Οκτ 2024 · The prognosis for individuals with Gilbert syndrome is excellent, and the condition does not lead to significant liver disease. However, patients with Gilbert syndrome may have an increased risk of drug toxicity when exposed to medications that affect bilirubin metabolism.
Mortality rates were around half in patients with Gilbert's syndrome after accounting for sociodemographics and general health indicators (adjusted mortality rate ratio: 0.5 [95% confidence interval; 0.4-0.7; P < 0.001]).
Gilbert’s syndrome manifests as mild unconjugated asymptomatic hyperbilirubinaemia, usually found in young adults during routine laboratory check-ups or after an intercurrent illness. The diagnosis is typically made per exclusionem, i.e. by excluding other causes of hyperbilirubinaemia.
12 Οκτ 2024 · Gilbert syndrome is associated with a life expectancy. In fact, studies have shown that people with the condition may have a lower risk of atherosclerotic cardiovascular disease (ASCVD). Bilirubin was once thought to be toxic to the body’s cells.
13 Ιουλ 2022 · No treatment is needed. People with Gilbert's syndrome can lead normal, healthy lives. Life expectancy is not affected and life insurance is not affected. There is even some evidence that people with Gilbert's syndrome live longer and are healthier than people who don't have it.
Key learning points. Gilbert’s syndrome (GS) is the commonest hereditary unconjugated hyperbilirubinaemia. GS is a benign, self-resolving jaundice with otherwise normal liver function tests and absence of haemolysis. GS can coexist with other causes of unconjugated hyperbilirubinaemia, in particular hereditary spherocytosis/ thalassaemia.
