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1 Απρ 2021 · Glucose release from hepatocytes (and gut enterocytes) is represented by the balance between intracellular glucose-6-P synthesis from glycogenolysis, gluconeogenesis and glucose phosphorylation on one hand, and glucose-6-phosphate disposal into glycogen synthesis and glycolysis on the other hand.
17 Ιουλ 2023 · Glycolysis is the most crucial process in releasing energy from glucose, the end product of which is two molecules of pyruvic acid. It occurs in 10 successive chemical reactions, leading to a net gain of two ATP molecules from one molecule of glucose.
1 Απρ 2024 · In summary, our findings identify an intrinsic pathway that links glucose availability to lipid availability via glucose sensing by a Golgi PtdIns4P–ATGL–lipolysis pathway that...
Below we discuss the different pathways involved in lipogenesis and how they are altered in metabolic diseases, particularly NAFLD and type 2 diabetes (T2DM). Figure 1.
4 Μαΐ 2023 · The authors show that adipose de novo lipogenesis is supported by glucose, and the pentose phosphate pathway provides NADPH, while hepatic lipogenesis mainly uses acetate and lactate, with...
30 Ιουλ 2022 · Lipogenesis. When glucose levels are plentiful, the excess acetyl CoA generated by glycolysis can be converted into fatty acids, triglycerides, cholesterol, steroids, and bile salts. This process, called lipogenesis, creates lipids (fat) from the acetyl CoA and takes place in the cytoplasm of adipocytes (fat cells) and hepatocytes (liver cells ...
Original artwork by biolution GmbH. In both fetuses and neonates, the main precursors of lipogenesis are glucose, lactate and ketone bodies [84–86]. However, among these precursors glucose is the only one that adequately produces the main substrates needed to facilitate the whole pathway, as summarized in Fig. 4. Sign in to download hi-res image.
