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23 Ιαν 2023 · Therefore, leaving groups that form resonance structures upon leaving are considered to be excellent leaving groups. The following diagram shows sulfur derivatives of the type ROSO 3 - and RSO 3 - . Alkyl sulfates and sulfonates like the ones shown make excellent leaving groups.
12 Απρ 2011 · A leaving group is a nucleophile acting in reverse; it accepts a lone pair as the bond between it and its neighbor (usually carbon for our purposes) is broken. So what makes a good leaving group? Good leaving groups are weak bases.
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20 Ιουλ 2022 · best leaving group \(I\)- > \(Br\)- > \(Cl\)- > \(F\)- worst leaving group This trend is evident when you compare the relative rates of \(S_N2\) reactions of four halomethanes with a common nucleophile and solvent: iodomethane reacts fastest, fluoromethane the slowest.