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1. www.uptodate.com › contents › gout-treatment-of-flaresGout: Treatment of flares - UpToDate

   www.uptodate.com › contents › gout-treatment-of-flares

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   20 Σεπ 2024 · As an example, a randomized open-label trial of 399 participants with gout flares compared naproxen 750 mg oral dose followed by 250 mg every eight hours for seven days with low-dose colchicine 0.5 mg three times daily for four days; at seven days, there was no difference in pain intensity, but naproxen caused fewer adverse effects (eg ...

2. www.uptodate.com › contents › treatment-of-gout-flaresTreatment of gout flares - UpToDate

   www.uptodate.com › contents › treatment-of-gout-flares

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   30 Νοε 2023 · Where 0.5 mg is the only available form, an initial dose of 1 mg may be used, followed by 0.5 mg one hour later for a total of 1.5 mg for the first day of therapy. Subsequently, the colchicine dose may be reduced to 0.5 mg twice daily until 48 hours after the resolution of the flare.

3. www.racgp.org.au › afp › 2016RACGP - The management of gout: Much has changed

   www.racgp.org.au › afp › 2016

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   The salient points include the need to treat gout to a serum urate target, the ability to start allopurinol during acute attacks, the need to treat with prophylactic anti-inflammatory drugs for adequate time periods, and the availability of a new urate-lowering drug on the Pharmaceutical Benefits Scheme (PBS).

4. www.jmcp.org › doi › 10Cost Comparison of Urate-Lowering Therapies in Patients with Gout...

   www.jmcp.org › doi › 10

   29 Μαρ 2016 · Gout flare prevention relies heavily on urate-lowering therapies such as allopurinol and febuxostat, but clinical decision making in patients with moderate-to-severe CKD is complicated by significant comorbidity and the scarcity of real-world cost-effectiveness studies.

5. ard.bmj.com › content › 76/1/292016 updated EULAR evidence-based recommendations for the...

   ard.bmj.com › content › 76/1/29

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   1 Ιαν 2005 · Importantly, other modifiable risk factors have been identified since 2006, specifically sugar-sweetened drinks, foods rich in fructose and orange or apple juice.38–41 In contrast, according to epidemiological studies, consumption of coffee,42–44 and cherries is negatively associated with gout, and eating cherries may reduce the frequency ...

6. www.aafp.org › pubs › afpManagement of Gout: Update from the American College of...

   www.aafp.org › pubs › afp

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   Urate-lowering therapy is recommended for patients with two or more gout flare-ups per year, tophaceous gout, or damage attributable to gout visible on radiography. Consider starting...

7. evidence.nejm.org › doi › fullComparative Effectiveness of Allopurinol and Febuxostat in Gout...

   evidence.nejm.org › doi › full

   3 Φεβ 2022 · This multicenter, randomized, double-blind, noninferiority trial was designed to examine the comparative efficacy and safety of allopurinol and febuxostat when appropriately titrated in...