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7 Ιουν 2024 · Gonorrhea infection is a common STI caused by Neisseria gonorrhoeae, a gram-negative diplococcus bacterium that is closely related to other human Neisseria species. Men typically present with a urethral discharge; women are often asymptomatic, but may have vaginal discharge.
The presence of gram-negative intracellular diplococci (GNID) or purple intracellular diplococci (MB or GV) on urethral smear is indicative of presumed gonococcal infection, which is frequently accompanied by chlamydial infection.
gram-negative diplococci are diagnostically significant for gonococcal infection only in a urethral smear from a man; women may have saprophytic gram-negative diplococci in the characteristically has: (1) an absence of inflammatory cells; (2) a decreased number of gram-positive lactobacilli morphotypes; (3) an excess number of pleomorphic gram ...
31 Ιουλ 2024 · Gram staining of clinical specimens (including sterile and nonsterile body fluid specimens, biopsy specimens, and positive culture specimens) is useful for guiding empiric clinical management for bacterial infections pending definitive culture data and/or molecular data.
31 Ιουλ 2024 · The presence of typical gram-negative intracellular diplococci and polymorphonuclear leukocytes on Gram stain from a specimen collected from a symptomatic male establishes a diagnosis of...
Gram stain may reveal gram-negative intracellular diplococci if N. gonorrhea is the cause. Appropriate tests for gonorrhea and tests for chlamydia must be done, but treatment should not be delayed because ascending infection may occur.
If your test result reveals a negative Gram stain or “no organism seen,” it usually means that there are too few bacteria present to be able to be seen using the Gram stain method. Bacteria might still be detected by culture if a culture is performed on the specimen.
