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Apart from the systemic effects of potassium overdose, extravascular leakage of potassium chloride, or direct dermal injection, can lead to local necrosis and chemical burns caused by ischemia due to vascular constriction [15].
Potassium chloride intravenous injection is used in suicide attempts and lethal procedures for state-sanctioned punishment. Owing to its relatively high concentrations in hemolyzed blood (25-80 mM) compared to serum (about 4 mM), it is difficult to conclude potassium poisoning by postmortem analysis ….
It takes a much bigger dose of ingested potassium to produce toxicity in a person with normal renal function than in patients with compromised renal function. Potassium toxicity manifests in significant, characteristic, acute cardiovascular changes with ECG abnormalities.
27 Νοε 2012 · In acute overdose situations due to ingestion of potassium salt, the general principles of treatment for overdoses should be followed. Calcium chloride infusion, dextrose and insulin in water, and correction of acidosis with sodium bicarbonate are helpful in controlling the acute, life-threatening cardiac arrhythmias.
28 Μαρ 2019 · When serum potassium reaches 7 mEq/L or higher, there is significant risk for acute life-threatening complications. Symptoms include paralysis or muscle weakness, chest palpitations, arrhythmias, and gastrointestinal distress.
13 Μαΐ 2023 · Brain oedema, lung oedema, congestion of lung, liver and kidney, severe dilation of heart chambers, mild steatosis in the liver and hypovolemic spleen were considered as manifestations of hyperkalaemia. Lethal hyperkalaemia due to potassium chloride overdose was considered as cause of death.
23 Ιουν 2017 · Potassium chloride is widely used to treat hypokalaemia, the condition where potassium levels in the body are too low, as can happen with seriously ill patients who then face the possibility of a heart attack.
