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  1. Endothelial cells (ECs) are sentinels of cardiovascular health. Their function is reduced by the presence of cardiovascular risk factors, and is regained once pathological stimuli are removed.

  2. Endothelial cells are important constituents of blood vessels that play critical roles in cardiovascular homeostasis by regulating blood fluidity and fibrinolysis, vascular tone, angiogenesis, monocyte/leukocyte adhesion, and platelet aggregation.

  3. 5 Οκτ 2022 · Vascular endothelial cells form the inner layer of blood vessels where they have a key role in the development and maintenance of the functional circulatory system and provide paracrine...

  4. Endothelial cells are located on the intima – which is the inner lining of the vasculature and they control vascular function by responding to various hormones, neurotransmitters and vasoactive factors which affect vasomotion, thrombosis, platelet aggregation and inflammation [1].

  5. 13 Μαρ 2007 · Endothelial cell activation leads to increased expression of inflammatory cytokines and adhesion molecules that trigger leukocyte homing, adhesion, and migration into the subendothelial space, which are processes fundamental to atherosclerotic lesion initiation, progression, and destabilization.

  6. 24 Σεπ 2020 · Our study defines the cellular and molecular signatures of the adult healthy heart, and enables functional plasticity in response to varying physiological conditions and diseases.

  7. 5 Σεπ 2024 · It discusses the diverse functions of endothelial cells throughout the vasculature’s life cycle and advocates for understanding the vasculature as a dynamic and interactive organ system, with implications for preventive regenerative health interventions.

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