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increase the overall efficacy of a heartworm prevention program in laboratory studies involving known resistant heartworm isolates by providing control of the arthropod vector of heartworm. In addition, AHS recommends reduction of exposure to mosquitoes through standard environmental control of mosquitoes and their breeding environments, and when
For detailed information on heartworm biology and life cycle, please refer to the complete AHS Current Canine Guidelines. HEARTWORM PREVENTION • The FDA-approved heartworm preventives currently marketed (ivermectin, milbemycin oxime, moxidectin, and selamectin) belong to the macrocyclic lactone (ML) class of drugs.
The overall goals of treatment are to safely and successfully eliminate current adult and immature heartworms, prevent new infections and minimize treatment related complications in your dog. The recommended treatment consists of the 5 steps outlined below.
By adding a layer of mosquito repellent insecticide to macrocyclic lactone use, the transmission of D. immitis microfilariae drops significantly—even with resistant strains of canine heartworm, such as JYD34 (short for “junk yard dog 34”), which is one of six known resistant strains.
Heartworm antigen testing is the most reliable method of confirming the eficacy of adulticidal therapy. Melarsomine, administered via deep intramuscular injection into the belly of the epaxial lumbar muscles between the 3rd and 5th lumbar vertebrae, is the only adulticidal drug approved by the FDA.
For a detailed review of the heartworm life cycle and transmission of heartworm infection, please refer to the complete Canine Guidelines. HEARTWORM PREVENTION The AHS recommends year-round heartworm prophylaxis for maximal effectiveness. If seasonal treatment is chosen, administration should begin at least one month prior to the anticipated start
These guidelines, developed by the European Society for Dirofilaria and Angiostrongylus, are based on the latest information and include up-to-date recommendations for the prevention, diagnosis, and clinical management of feline heartworm disease (HWD).
