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1. www.ncbi.nlm.nih.gov › pmc › articlesHelminth Therapy for Immune-Mediated Inflammatory Diseases:...

   www.ncbi.nlm.nih.gov › pmc › articles

   21 Ιαν 2022 · Since helminth infection is not an appropriate treatment direction due to the complex immunoregulation and safety concerns, one of the new therapies is to harness the immunoregulation induced by the identified helminth-derived molecules using immune indexes as a guide.

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     Thioredoxin peroxidase-2: Trichinella spiralis: Macrophage→...

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     Figure 3. Open in a separate window. The pathogenesis of...

2. academic.oup.com › ibdjournal › articleHelminth Regulation of Immunity: A Three-pronged Approach to...

   academic.oup.com › ibdjournal › article

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   26 Αυγ 2016 · In the authors' opinion, helminth therapy can be approached from 3 broad perspectives: (1) use of viable ova/larvae, (2) administration of helminth-derived extracts or purified molecules, and (3) cellular immunotherapy with helminth extract/antigen-pulsed immune cells.

3. pubmed.ncbi.nlm.nih.gov › 34579797Use of helminth therapy for management of ulcerative colitis and...

   pubmed.ncbi.nlm.nih.gov › 34579797

   The aim of this systematic review was to investigate whether there is evidence to support the use of helminth therapy for the management of Crohn's disease and ulcerative colitis. Four databases (PubMed, Embase, Medline and the Cochrane Central Register of Control Trials) were searched for primary evidence in the form of clinical studies.

4. pmc.ncbi.nlm.nih.gov › articles › PMC4374592Human helminth therapy to treat inflammatory disorders- where do...

   pmc.ncbi.nlm.nih.gov › articles › PMC4374592

   Several studies in animal models have demonstrate that intestinal helminth infections are able to inhibit the development of intestinal inflammation (reviewed in [14,15]) and the first clinical studies of helminth therapy in humans started some 10–15 years ago with the use of the pig whipworm Trichuris suis.

5. www.ncbi.nlm.nih.gov › pmc › articlesHarnessing helminth-driven immunoregulation in the search for...

   www.ncbi.nlm.nih.gov › pmc › articles

   14 Μαΐ 2020 · Studies of live helminth therapy in mice and larger animals have convincingly shown that helminths and their excretory/secretory products possess anti-inflammatory drug-like properties and represent an untapped pharmacopeia.

6. www.ncbi.nlm.nih.gov › pmc › articlesPotential treatment of inflammatory bowel disease: a review of...

   www.ncbi.nlm.nih.gov › pmc › articles

   Studies using helminths like Trichuris suis or Necator americanus showed that these helminths are safe and may be effective therapeutic approaches for the control of IBD and other immune diseases. The aim of present review was to exploring the therapeutic use of helminths for the control of IBD.

7. www.researchgate.net › publication › 354905861_The_use_of_helminth_therapy_forThe use of helminth therapy for management of ulcerative colitis...

   www.researchgate.net › publication › 354905861_The_use_of_helminth_therapy_for

   28 Σεπ 2021 · The aim of this systematic review was to investigate whether there is evidence to support the use of helminth therapy for the management of Crohn's disease and ulcerative colitis.