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21 Σεπ 2018 · Hemoglobin C (Hb C) is a common structural hemoglobin variant. Persons with hemoglobin C trait (Hb AC) are phenotypically normal, with no clinically evident symptoms, while those with...
30 Νοε 2021 · Hemoglobin C disease is a blood disorder that can cause fatigue, weakness, and anemia. It occurs when a person inherits two copies of hemoglobin C genes from their parents.
29 Μαΐ 2023 · Hemoglobin C trait (HbAC) is clinically silent. Hemoglobin C disease (HbCC) is also a mild disorder, and most people do not have any symptoms. But some patients may experience mild hemolytic anemia and hence may complain of symptoms like fatigue, lightheadedness, weakness, and paleness of the skin.
Hemoglobin C, S-C, and E diseases are inherited conditions characterized by gene mutations that affect the hemoglobin (the protein that carries oxygen) in red blood cells. These red blood cells are destroyed more quickly than others, resulting in chronic anemia.
Hemoglobin C Disease - Etiology, pathophysiology, symptoms, signs, diagnosis & prognosis from the MSD Manuals - Medical Professional Version.
Patients with hemoglobin C disease may have mild to moderate splenomegaly, cholelithiasis, or other signs of chronic hemolysis. Pain crises are not a feature, and life span is not decreased.
Hemoglobin C disease (HbC) is a hemoglobinopathy characterized by production of abnormal variant hemoglobin known as hemoglobin C, with no or mild clinical manifestations (hemolytic anemia).