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16 Απρ 2023 · The most common benign cause is PHPT, where patients are usually asymptomatic and have a long-standing history of mild hypercalcemia. Serum calcium levels greater than 13 mg/dL on initial presentation should raise suspicion of malignancy as the cause of hypercalcemia.
21 Σεπ 2018 · This article reviews the causes of hypercalcemia in the patient with cancer and describes the diagnostic steps and treatment options for the most common causes of hypercalcemia. Many organs are involved in the regulation of calcium.
Hypercalcemia of malignancy is a common finding typically found in patients with advanced stage cancers. We aimed to provide an updated review on the etiology, pathogenesis, clinical presentation, and management of malignancy-related hypercalcemia.
21 Σεπ 2016 · Hypercalcemia can occur in those with malignancy and an additional etiology for hypercalcemia such as primary hyperparathyroidism or granulomatous diseases. This paper reviews the cancers associated with hypercalcemia and their proposed mechanisms, nontumor-mediated hypercalcemia, as well as diagnosis and treatment strategies for each condition.
Hypercalcemia of malignancy (HCM) affects 2% to 30% of patients with cancer and is associated with high morbidity and mortality. Symptoms range from fatigue, constipation, polyuria, and polydipsia with mild-to-moderate hypercalcemia (mild: serum calcium [SCa] level of 10.5 to <12 mg/dL; moderate: SCa level of 12 to ≤14 mg/dL) to cognitive ...
Hypercalcemia is defined as a condition in which the serum calcium level is >10.5 mg/dL (the upper limit of normal) or the ionized calcium level exceeds 5.6 mg/dL. The consequences of abnormally high serum calcium can range from asymptomatic to life-threatening.
21 Δεκ 2022 · People with high blood calcium, also called hypercalcemia, have above-normal levels of calcium in their blood. Certain types of cancer can also cause high blood calcium. This usually occurs late in the course of the cancer and is referred to as hypercalcemia of malignancy (HCM).
