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In dogs and humans, recent dramatic alterations in healthcare and social structures have allowed increasing numbers of individuals in both species to far exceed their species-adapted longevities (by 2–4 times) without allowing the time necessary for compensatory natural selection.
Biologically, γGT is very sensitive for the diagnosis of liver injury, although enzyme induction can lead to loss of specific-ity for damage and it has poor specificity for particular aetiologies.
The life expectancy of a dog with Cushing’s disease can vary depending on several factors, including the severity of the disease, the age and overall health of the dog, and how well the disease is managed. On average, dogs with Cushing’s disease can live for 2-3 years after diagnosis, but some dogs may live longer with proper treatment and care.
14 Νοε 2021 · Whilst there are relative predictors for cardiovascular disease (metabolic syndrome, hyperlipidaemia and diabetes), cancer risk profiling usually relies on clinical or family history and is generally less robust by underwriting standards.
31 Ιαν 2023 · A greater association between higher serum GGT level and increased risk of CVD-, cancer-, respiratory disease-, and liver disease-specific mortality was noted among men and younger...
Given its cellular role in antioxidant function, it has been investigated as a surrogate biomarker of oxidative stress. It has also been found to be a predictor of mortality across a spectra of non-hepatic disease pathologies, from metabolic and cardiovascular risk to chronic kidney disease and neoplasia.
1 Φεβ 2023 · Weights ranged from 2.5–98.0 kg (Fig 4), with a mean of 30.3 kg and a median of 30.6 kg (Table 1). In general, as the weight of the dog increased, the median age at cancer diagnosis decreased; dogs weighing 2.5–5 kg had a median age at cancer diagnosis of 11 years, compared to 5 years for dogs ≥75 kg.
