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3 Ιουν 2019 · High globulin levels in dogs. When a dog's globulin levels are elevated, this is known as hyperglobulinemia and it is indicative of some type of disease process or condition that is stimulating the dog's immune system. The top possible causes for this can be chronic inflammation, chronic infectious diseases, allergies and even cancer.
12 Ιουλ 2023 · A high level of globulin in a dog’s blood, known as hyperglobulinemia, can be indicative of various underlying health conditions. It is essential for pet owners and veterinarians to understand the significance of elevated globulin levels and the potential implications.
6 Νοε 2020 · Hyperglobulinemia – an elevation of globulins – is a relatively common biochemical abnormality found in cats and dogs. Perhaps the most common reasons for globulins to be increased are dehydration and chronic inflammation (for example, associated with skin conditions).
28 Σεπ 2022 · A high globulin level in a dog's bloodwork indicates that their immune system is working overtime. They may be potentially battling infection or inflammation. Cancer, heartworm infection, and dental disease all cause an immune response, which can result in elevated globulin levels.
17 Ιαν 2024 · Globulin (GLOB)—Elevated globulin levels may suggest an an inflammatory condition, certain infections, or cancer (e.g. multiple myeloma or B-cell lymphoma in dogs). Minerals—calcium (Ca) and phosphorus (P)
Elevation of gamma globulins indicates immune system reactivity and may be polyclonal or monoclonal in nature. By contrast, hypogammaglobulinaemia in an animal with inflammatory or infectious disease might suggest failure of the immunological response (primary or secondary immunodeficiency) and trigger further investigation of this phenomenon.
For small animals, a typical panel includes total protein, albumin, globulin (calculated as the difference between the first two analytes), urea, creatinine, ALT, and alkaline phosphatase (ALP). In addition, a yellow color seen in the plasma should be considered an indication to measure bilirubin.