Αποτελέσματα Αναζήτησης
30 Οκτ 2023 · This article will review the embryology of the bone marrow as well as its histology. Additionally, the constituent cell lineages and their function will be discussed, together with clinically relevant processes and pathologies.
It is comprised of hematopoietic cells in various stages of development, supportive reticular connective tissue, and sinusoidal capillaries. Hematopoietic stem cells give rise to red blood cells (erythrocytes), white blood cells (leukocytes), and platelets (thrombocytes).
Here, 3D bone marrow models, their fabrication methods (including 3D bioprinting) and implementations recapturing bone marrow functions in health and diseases, are presented. The red bone marrow, located in the cavities of the trabecular regions in long bones, represents a complex blood and bone cell-producing organ.
In general, decalcified, paraffin-embedded, hematoxylin and eosin (H&E)-stained sections of bone marrow, the more mature stages of the erythroid and myeloid cells, adipocytes, mast cells, and megakaryocytes can be identified, but stem cells, immature myeloid, erythroid, lymphoid, monocytoid and stromal cells cannot be identified consistently.
Copyright and License information. PMCID: PMC7114821 PMID: 22285155. Bone marrow evaluation is indicated when the routine examination of a blood smear has failed to provide an answer to the question: What is causing an observed hematologic abnormality?
learn how to examine the cells in red bone marrow smears. understand what developing progranulocytes, myeloblasts and lymphocytes look like. identify the following stages in the formation of erythrocytes, neutrophils, and eosinophils and understand why the cells change in appearance as they mature:
Bone marrow is a specialized connective tissue composed of developing blood cells within a supportive stroma of reticular tissue. It is found between the trabeculae of the spongy portions of bones. MHS 304 Bone Marrow. H&E. Bone Marrow Smear.
